The Serial Port is harder to interface than the Parallel Port.
In most cases, any device you connect to the serial port will need the serial transmission converted back to parallel so that it can be used.
This can be done using a UART.
On the software side of things, there are many more registers that you have to attend to than on a Standard Parallel Port. (SPP)
preview:
http://www.beyondlogic.org/serial/serial.htm
7/10/2002